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 Kibow science and technology for kidney failure patients |
Kibow's science is based on the principle of "Enteric Dialysis®" -- the process by which colon-friendly, non-pathogenic microbes consume uremic toxins or metabolites. In a healthy patient, this process already occurs to a limited extent. However when kidney health is impaired, the normal bowel flora cannot metabolize and clear the excess toxins left unprocessed by the kidney.
Our lead products, Kibow Biotics®, ideal "cocktails" of GRAS (Generally Recognized As Safe) status microbes specially screened and selected for their high affinity and capacity for utilization of uremic toxins (urea, creatinine, uric acid, various carcinogenic amines, guanidine and indole metabolites, phosphate and others). |
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| Introduction to probiotics |
| Probiotics are live microbial food ingredients that alter the enteric microflora and help maintain it in a healthy condition. Some of the better known probiotics include the lactobacillus species, the bifidobacterium species and yeasts. When ingested, probiotics may beneficially affect the host by improving the balance of the intestinal micro flora. Probiotics have a long history of safe application dating back to biblical times with mention of dairy products from cultured milk. Soured milk and other cultured dairy products such as kefir, koumiss, leben and dahi were used for therapeutic purposes long before microorganisms were discovered. The term probiotics was founded by Dr. Élie Metchnikoff, Nobel Laureate (1908) and Director of the Louis Pasteur Institute. He recognized and spoke of the benefits of consuming Lactobacillus bulgaricus and Streptococcus thermophilus in yogurt. Today probiotics are used in many food products like yogurt, lactic acid bacteria milk, etc. Probiotics are generally known for their antimicrobial, immunomodulatory, anti-carcinogenic, anti-diarrhea, and anti-allergenic and antioxidant activities. |
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| Some of the commonly known probiotics used are: |
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Bifidobacterium sp. |
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Lactobacillus sp. |
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Lactococcus sp. |
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Streptococcus thermophilus |
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Saccharomyces boulardi |
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Enteric dialysis®
The development of target-specific probiotics composed of bacteria well characterized for their health enhancing capabilities has accelerated in recent years. At Kibow Biotech Inc. we are proud to be involved in extensive research on probiotics and their use in the application of gut based uremia therapy now termed as Enteric Dialysis®. |
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| What are prebiotics? |
| Prebiotics are defined as non-digestible food ingredients that may beneficially affect the host by selectively stimulating the growth and/or activity of a limited group of bacteria in the colon. Prebiotics are essentially oligosaccharides. They stimulate the growth of bifidobacteria and hence are also known as bifidogenic factors. The action of prebiotics may result in anti-carcinogenic, antimicrobial, hypolipidemic, glucose-modulatory, anti-osteoporotic activities. They have also been known to improve mineral absorption. |
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| Examples of prebiotics are : |
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Fructo-oligosaccharides |
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Lactulose |
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Inulins |
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Pyrodextrins |
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Isomalto-oligosaccharides |
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Soy oligosaccharides |
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Lactilol |
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Transgalacto-oligosaccharides |
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Lactosucrose |
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Xylo-oligosaccharides |
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Kibow biotics®
Synbiotics or pharmabiotics is the functional combination of both pre- and probiotics. At Kibow Biotech Inc, we have used prebiotics and probiotics in synergy to develop Kibow Biotics®. This generic formulation is used in Enteric Dialysis®, a functional synbiotic technology which may help to slow the progression of kidney disease. |
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further information on Kibow Biotics® please
do not hesitate to contact us. We would be pleased
to answer any of your queries. |
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